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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd4bd378c36a474c0aaf4c1256fa3e65d8ede17a639b12c3d23f423d53fe0110f' 
  AND token = 'Ek6CsqTljLEJClO6b2+lE5QMz3DmM+A52DI1xu0Yo10=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}