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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ea2f9802e8e0e0b40752677a0b9bf8d4dee15e6359f330038db4e39d00537b6f' 
  AND token = 'hkT6atm8IxKiwHbiJ/+AN5gPinuS8mEhhlbgrPtUcM4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}