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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2ab5b998c3e8f4a876540b195a6ef285a64e1de02a3fbbf855a58429b3fea962' 
  AND token = 'VN8gOY39b2D2hvdxVkMr5TWd+BK1y0owX/WC3SmBcPE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}