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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '748e940babdcaa9d2abdc99549a7be0af742958de33e71a134189ebe7ea1c22f' 
  AND token = 'oRXCPq/fz0Na1okF/jR+LbyN2MB4rELzjX0Pr2Hnqs0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}