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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2da9c13df343f8d8f97d42bc0cf485a289d80a5d1d79e868e64685c2817e8f2d' 
  AND token = 'w5GCLTB3IAcFfpD8RVO3iBumL6En/D3e8uDPr7hoJJ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}