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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '319db4947677c1a29b10b914204fa207ac424ca0a0e3d8a2522e2c16980895d6' 
  AND token = 'b2gy7qOxfCNw8k8LL1+M5UqNRCF+2WpsUh0SYw57JZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}