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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '88e1ca160a8f01d9f364e5cf07902ae7d8b4ec282529ad50411cd18a9382fd48' 
  AND token = 'KE3O5ZPVtVSeQhJtuzZQ5/H5A1xE0p3BTzSREI4MoFY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}