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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5e2a997eda66fc6725579217e23d4fbb43af5ea7393eac200a2312855b2aaa80' 
  AND token = 'cTl1nbGvytGmazaLB0/9NowGqj3UHIKPbn7/1sN/9XU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}