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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3ec4e2d696af0c6811e65c1a230d8a628b77b3d6021061fbf766096652e06a47' 
  AND token = '4UFB/+/F8kwu1YVBiyIz77SGGTeGmf3Xs5fcT/6ZxnQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}