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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '29b5192b37661c33e200c527ccd4017c51fa4eb506115700775304444d229d34' 
  AND token = '69zV8omDXjEkE15BXNm2MtWFZqqmlpU1xDvEYsxC474=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}