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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6a915ca48c65d8b5e823b8a94b7d50d7a847e97e46d168b102ca77b04746d50f' 
  AND token = '/KDPipylwpMuu48GiNW9S8AoVSOslSTBc5eot7FIluU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}