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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '538f46edbe39f9bcbe7d1700be4e3fcf99b64654ce5b398036046a609f32b3c8' 
  AND token = 's2cjB8kq+tAHEgJbbUHFxcoXHT3yMW2ovw3t/bnAA4U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}