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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd21224706029c55c945338c025c45eaa4d9a6f77be087264e106592760d983f5' 
  AND token = 'RwYioHWObfSCiqNBSytesD+/mkkRm2NM8vcKxTWJbAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}