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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '46b965c803fe1fbfe1a1ff1dd2c0b82fe5ec120a2ceaa54174c4df9dd22aa7fc' 
  AND token = '2FLFtoMj4llz1Zml7ond8ge9E0eC7CSUjPnf6199vbY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}