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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e1b289fe42b11bf45af67e8f2321dc53fe0d2292e05bbd7daf5fb945ed00d36a' 
  AND token = 'e1rPzJBunaOLc5D1NLAq5xuVugYA+MXVJX1E+cqruLw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}