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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e64fbb34ce3c13ee6df6247dbd0a388e7e229335847974f811beaa4ac007e7cb' 
  AND token = 'yk/KAlz18G1Ws2uWySLaYCZ3Ysp+KtZllkjYy4m/RzU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}