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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6dec6e8e49ce0dcb689d307ebdbcbe13f71ba3f7e4227e2f017b86852753b240' 
  AND token = 'JB5E4NaJEouFKPCglOsZvFJd4d8/f0JzNCiCO4GGgBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}