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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c70ab7f3e8a75fbec2591f353adea1db057c7ce827904175923f27df64e62634' 
  AND token = 'yEg6ZHcI+C4ynAD0o7gv1J8kddLBQCpb5ZbAzijiZtc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}