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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1d5bf39927487541c3b559927ee5d580c5a05fa21654e6ce10b14288850a6603' 
  AND token = 'EDudxtGhRKPAPSSofMcApderQ262+sHKD0CWkR0o4tU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00074

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}