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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '787fb058f21f0af11a3dc34b7c225220bb3a04903aaa5f2663fefb5dbc139546' 
  AND token = 'UVQEx/Ptob+c4aBM0GdqybpBZ2mzU5RctkWK8ttotFM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}