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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f6c6c21ae9cef9384faaffce379543ffb7f238713010313ad838a395b6be93f4' 
  AND token = '6hUb0K8gqvhDxInj8Q3bQ6dfOBVXJIUROCAPdv5TML8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}