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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5125e828bee9466fd6df6c8d473bf5cb78151ec6c9d0225a28d6427913fdfbab' 
  AND token = '4C3/NsMXQderShnJ9vkuwPMuxMcMuAkpdo9OiEgoJR8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}