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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'cd287800dece54571ea6d74869aa41cfb4cc10a306227a678f1ec528afa91d48' 
  AND token = 'WruGMFTbfyWfLmAmAMCBASLxNdTiFky8myHk5ws8nIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}