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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '7e648e101263760c65dd7ee7e957f3433ce0534f58ae88d55a98ba2520b5454e' 
  AND token = 'DQEei4a3tnFuyzyuwTSzzi6/9PT7iW90qLxV0uC6guA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}