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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '9533d289c5c5c131df476ffea98d06feca7d3b95f5633f73c09be4eaf6655896' 
  AND token = 'yXysEwamCmF4njkq1w8VwmKOtWowqTQ2j3Ff7PbeTNs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}