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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2160b36fdeceb15f13f9b36a25fcd63b4930dcf708bdfa5752c73a969647c1c1' 
  AND token = 'qwl9t6OiT0qapJPOCCfAEdUcS8RZzuqg4kFDUlcJYUg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}