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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ba87df546b319f909d5e5c4581c93f794101df824279f44e7ad5471950e3005c' 
  AND token = 'uzg2TH8gNe50p8VbSh1xZFKIe9L0C6IOQsSaIw38TrQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}