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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2a2cf2aba3ffdafa8a70129bfd78f72c53bba8e9b4821073f5893692d5267072' 
  AND token = 'cFbISLGd2L9j7k4ToXcw4izASgxAFm0h+1Jmvvf4i0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}