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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8c68d4d4f563c49cd4d401b9bd06b64daa5df582ba0793a726c413fcdf9cacbc' 
  AND token = 'YEyxlzvNo4xFzdVzOp+idvFks2XPJvFYral9moprX4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}