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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c5973882e6c8dc5f75e48db823f356b9a7dce8d70a20413c9de8804909c6b08b' 
  AND token = 'qkj6Tez48F6bUbZUpPkFXbi3C2gpMkAUsTiS8j0BANQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}