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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ca87b957b788662f8f24b67b7b5867fc78eafb2557861a4b381b417cbd474507' 
  AND token = '3cFejX9/0GGz1aXufZ7eU7zaT2GyuIQCvW3N/ZW2dVA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}