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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '23f2bff1e31d1b76eb716407b9f75bd2999d3d0e317dbde94c9ea434caf2ff05' 
  AND token = 'L5MiMx/wAK3bXVnBdPuXZZvP2Urq1e8Ht2/3CDoeJQA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}