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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'de1b0288bca286d6c3f4407c043b877b02d18b4f8b23190369e6bcdc49f925a8' 
  AND token = 'Mqw/HkIMGB0r9rdiQa+k4tcV5b9OgN41cqwzkk0BRyw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}