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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '385423495558bf7af56aa9221f1da77e88a2438c4d51b300e4e0b4f3bddfc536' 
  AND token = 'oJbFO5vlvi6HHhEhEwOaJbUdMftIQWs9zpiE+QIGu7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}