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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6e1059a84893d2490c14a322c1d478ca70880e4c43ada8750730c01b4f2f6d64' 
  AND token = 'IxokL+FJi4Sw+gPUucyhgOWAbNJ3c2TMoFuVn0WUVJk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}