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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '38c0fb7ee97f5962d67d91073b492e66a21343cf34bb3c0c6fbae16050e4fc7b' 
  AND token = 'V/+rVVOlxp2KmbAuhEpNmHmvx6l08YfyfhPis80VXFQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}