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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '111e9f8a5b5121328f248e4e96993111ac86d2d252e3fb1aad295cc128d6d0a5' 
  AND token = '5b6KBSjNAnQaxpO27n2ZIaIvWvHKTbb72K//pBVn4L0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}