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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2b7a122b721a60a4705e531c839dbb5021bbb33127e2b475feb3b246648909ae' 
  AND token = 'qlAzoaWZHceFUS0iZXJvEgdO6oqUVdJXFy3rlKkuzoM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}