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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd7b68358a48e315618c218cc52d07819914739eec73a4854d2614eaee1eaa2a4' 
  AND token = 'frSeZTqWW80az3M6TGNamtgiWm099T1rSArRgtm68WU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}