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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '7b7439f6848406a8c31fcf0ba7e9f499ec4eb79266188d7218040de069c42f70' 
  AND token = 'N2p6MtrqF4r/3LBWKYaqu20qtoikyWQOxMijbm4KzKc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}