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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2262a82dbc5241a3f3b5f3195af47df06ddd7f85902c410174292620d0f7d603' 
  AND token = 'eS25pf4Pom8I04dS/AYNIoNzygZrtNb9ZFuqswT2uc8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}