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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '854b16325a54729c8370c3b7393d52fff18e3869704ba6de09090e8be3b6177b' 
  AND token = 'NkiLBHSPhxNQHswOVHfRNdnPSiHs+RpbI1QqMWfjOqE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}