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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0a25e219634274ed2a0afd20212863e990eed2caca0350023c6f0ef8b2851361' 
  AND token = '2UK5ObuhaOnaivNj1nn/fapEog4tfWftvg33HZQ3DR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}