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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a681e6df3c7c1ccff63d5929d89343c232d427ed43296702cd0223062141ba3e' 
  AND token = '2jAs3rqERqW8i6vM8nt3re5B0Ecvz2c1FKK7vFK4XB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}