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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ef5ee73be69426fb60d1162120c4329d0073a11444a16e09c3c05840f0f0a714' 
  AND token = 'pXL2tnpTj9x6e1SC0XYdKrGqwDGeHZd8OTaZIP/xukg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}