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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '04dd100651eb9906e1aa10c5647152b614a9f9a0e0cc1698f19af0647c43b757' 
  AND token = 'VSAQnbkQtnjexuZXMOJkZD9/6d7w59RQYCjdsSw3aXQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}