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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '41d649553f736367a815690e513a9c4b69ac911f31e7cf40880f1b190cc17c3d' 
  AND token = '3KgLQ9LCRcUQZX7kxmqWGgTn4z85EnKs42APC53FyQY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}