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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '18dd8f6408a598a8ce48ff1b44fda2fe51e8bfe6e9da95c780f47cbd068de5f4' 
  AND token = 'guPS+BQuw/Tk/JyxZpQs7e8zmeG3I+SP3ZACNWORQA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}