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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b483825a8207e64dbea5fabf122aa91f092213a3df30fccfe7bb15e942b666a5' 
  AND token = 'nkuYuc4ppLSadWLQVb9BzFhE3sU6uEV8bqP+z86SxG8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}