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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ec6b905bbcaf4b130e8677537e79f1d40f4e358394008f2fc4f44013e85901d1' 
  AND token = 'L+78poQ/bIdhRLBPkqThMyy1vU3Xbo2OLyYrbPBeT/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}